منابع مشابه
Ticlopidine, a new anti-thrombotic drug.
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A 21-year-old male presented to the emergency department after a 5-day history of recurrent vomiting and decreased urine output. History revealed ingestion of ibuprofen. During the diagnostic workup, the following was identified: white blood cell count 13.4 (×10(3)/mcL), hemoglobin 11.9 (×10(6)/mcL) with an MCV of 73 fL, hematocrit 34% and platelets were 31,000/mcL, sodium of 130 mmol/L, potass...
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Managing coronary thrombus is a challenging task and requires adequate knowledge of the various antithrombotic agents available. In this article, we will briefly analyze the risk-benefit profile of antithrombotic agents, with critical analysis of the scientific evidence available to support their use. Since thrombus consists of platelets and coagulation cofactors, an effective antithrombotic st...
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Electrospinning is an effective technique to prepare non-woven fibrous formulations with interesting properties that enable the encapsulation of various pharmaceutical agents. Targeted delivery of drugs, while preventing any side effects or toxicity, still remains a challenge, especially in the cardiovascular field and therefore, nano/ submicron fibers created by electrospinning have been inves...
متن کاملPlatelet GPIb complex as a target for anti-thrombotic drug development.
Specific inhibition of platelet function is a major target of anti-thrombotic drug research. Platelet receptors are both accessible and specific but have multiple functions often linked to a wide range of ligands. GPIb complex is best known as a major platelet receptor for von Willebrand factor essential for platelet adhesion under high shear conditions found in arteries and in thrombosis. Rece...
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ژورنال
عنوان ژورنال: Cardiovascular Pharmacology: Open Access
سال: 2018
ISSN: 2329-6607
DOI: 10.4172/2329-6607.1000231